Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length564 amino acids

Chemical FormulaC2672H4192N780O816S20

DescriptionStandard

        MIMATGYVLCLGDKTTCGGRIISGNPGRRAHSRPVARHGDIVTCGKHEGQYRITGGISFMTDVEGAERIPVAGTLDSVSGCPCRSGFIVTHYPAMKYESRSSGLTSSGGSPAVYGSMAGSGSALSSVAANAAKNVKTPVFAKSCLRGEGCNDAGQESEPHTNFARMAFYQAIPPADPASNYDVPQHAQSARKKKPAEDIPKPKKRSALYKWWFGNYEEVEYQRAAAAAASAANAQSALEGASVLGLIGGSAITSGTWAVSSATRLGAIAASGPGAPIAALLVGMMPGRLNEGEQDFIDRLRLEQMHEAPSRVRYTWENDSNSDAVPHGWHTPPGKDMVRVRKMEWDSSRNAYTFITEEDPRITIIWTPDSSGVNVPSNTGNHNPVRIPNPVVVDPLPEDTRIEATTTPAPEEKSFADYILILPIPDIPPIYVYLRNNPGQVTGKGQKVSGIWLSDANTGNGSPVPSQIADRLRGRTFENFDQFREAFWIEVSKDPELSRQFKGSNIINMKKGKAPATYREGRVGKRIKFEIHHIKPIGQGGEVYDVDNMGVATPRRHIDIHSNK
    

Molecular Weight60939.91 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 5.56

Charge Density (pH 7.0) 0.0119

GRAVY Index-0.46

Hydrophobic Moment 0.68

Boman Index-0.02

Instability Index44.31

Aliphatic Index 69.41

Aromaticity 0.0727

Extinction Coeff. Reduced 74830.00

Extinction Coeff. Oxidized 75205.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336476 VERIFIED: YES

Provenance & Taxonomy

OrganismErwinia sp. J316 [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli