Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC911H1434N252O249S8

DescriptionStandard

        PTPLPTAHEPMLLLTVTEFVANSAAFTYFTAGALRRNISSSMLPRRFPLQLKTKSMGVFAPQLQERYPDQPMELHLSARQQPLLSCHPDALHGTLFGSAEAFVVLPNTTRIPAFLLNIDANVTGKPTITRNRLGASVHLTDCVVRGSGAAYPQVKRLETLLKFGLWLFGVPWANSECCPHPRP
    

Molecular Weight20157.19 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)6.46

Net Charge (pH 7.4) 6.01

Charge Density (pH 7.0) 0.0353

GRAVY Index-0.02

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index47.81

Aliphatic Index 88.52

Aromaticity 0.0820

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7864.10

LogP -90.00

H-bond Donors 273.0

H-bond Acceptors 269.0

Rotatable Bonds 632.0

Heavy Atoms 1420.0

Ring Count 42.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419711 VERIFIED: NO

Provenance & Taxonomy

OrganismGeococcyx californianus (Greater roadrunner) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria