Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC81H120N22O30S9

DescriptionStandard

        DCQFCCGCCPDMSGCGSCCTF
    

Molecular Weight2170.53 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.32

Net Charge (pH 7.4) -2.64

Charge Density (pH 7.0) -0.1103

GRAVY Index0.57

Hydrophobic Moment 0.17

Boman Index0.18

Instability Index65.77

Aliphatic Index 0.00

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 814.91

LogP -13.25

H-bond Donors 35.0

H-bond Acceptors 37.0

Rotatable Bonds 65.0

Heavy Atoms 142.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094064 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus bruneus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)