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MYP_140689
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Basic Information
Glycomacropeptide
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
8 amino acids
C47H67N11O13
Standard
Sequence
DKVGINYW
Physicochemical Analysis
994.10 Da
5.83
-0.24
-0.45
-0.0301
-0.60
0.32
0.10
-46.66
85.00
0.2500
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
409.45
-1.72
14.0
13.0
30.0
71.0
3.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009189 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glycomacropeptide
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Glycosylation-associated glycomacropeptide context
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
25.35 μM
IC50
PaperThe Portuguese Paradox: Why do some inhabitants of Portugal appear to live so long when their diet is based on whey cheese? | Tavares, TG. et al. | DOI: 10.1016/j.foodchem.2011.09.052 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0061263 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
IC50
PaperAcute effect of whey peptides upon blood pressure of hypertensive rats, and relationship with their angiotensin-converting enzyme inhibitory activity | Tavares, TG. et al. | DOI: 10.1002/mnfr.201100381 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
RECORD: Rec_0064771 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
25.4 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0090508 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
15 mmHg
SBP decrease
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0104581 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
25.4 μM
IC50
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
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