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MYP_140672
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Basic Information
GBVA1(1-18)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
18 amino acids
C104H176N32O23S
Standard
Sequence
LLDCWVRLGRYLLRRLKT
Physicochemical Analysis
2274.78 Da
10.85
3.75
3.53
0.2083
0.04
0.92
-0.18
51.50
146.11
0.1111
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
925.19
-4.16
37.0
28.0
76.0
160.0
3.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
10 μM
IC50
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0017927 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV) JFH-1
PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0036632 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
hepatitis C virus(Jc1-Luc HCVcc):inhibition of virus entry in Huh7
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. J Virol. 2013 Feb;87(3):1649-1657. doi: 10.1128/JVI.02201-12. PMID: 23175359. PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0064940 VERIFIED: YES
Provenance & Taxonomy
Hepatitis C virus [Virus]
Virus-derived peptide
3052230;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Hepatitis C virus (Virus entry); Huh7.5.1
10 μM
RT-PCR
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. | Liu X, Huang Y, Cheng M, Pan L, Si Y, Li G, Niu Y, Zhao L, Zhao J, Li X, Chen Y, Yang W. | J Virol. 2013 | PMID:23175359 PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0083279 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 61.1%, E 0.0%, T 11.1%, C 27.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
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