Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length150 amino acids

Chemical FormulaC760H1236N218O224S6

DescriptionStandard

        METQRASLCLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEPGNFQRLRKKKERKKRQYYYTVLL
    

Molecular Weight17203.66 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)5.47

Net Charge (pH 7.4) 5.14

Charge Density (pH 7.0) 0.0365

GRAVY Index-0.59

Hydrophobic Moment 0.77

Boman Index-0.17

Instability Index38.65

Aliphatic Index 86.40

Aromaticity 0.0667

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7192.07

LogP -69.47

H-bond Donors 253.0

H-bond Acceptors 236.0

Rotatable Bonds 572.0

Heavy Atoms 1208.0

Ring Count 24.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417077 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal