Peptide Database

Peptide NameEsculentin-2SN1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC370H585N97O107S5

DescriptionStandard

        MFTMKKSLLFLFFLGTISLSLCEQERGADEDDGGEEVKRGIFSLFKAGAKFFGKNLLKEAGKAGAEHLACKAANQC
    

Molecular Weight8264.51 Da

Isoelectric Point (pI)7.70

Net Charge (pH 7.0)0.57

Net Charge (pH 7.4) 0.23

Charge Density (pH 7.0) 0.0075

GRAVY Index-0.04

Hydrophobic Moment 0.69

Boman Index0.07

Instability Index14.84

Aliphatic Index 77.24

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3299.22

LogP -29.79

H-bond Donors 116.0

H-bond Acceptors 114.0

Rotatable Bonds 290.0

Heavy Atoms 579.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146927 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvirana spinulosa [Animal]

FamilyFrog skin active peptide (FSAP); Esculentin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria