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MYP_140606
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Basic Information
GP-CS1=corticostatic peptide [guinea pigs, bone marrow, Peptide Partial, 31 aa].
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
31 amino acids
C164H262N54O41S6
Standard
Sequence
RRCICTTRTCRFPYRRLGTCIFQNRVYTFCC
Physicochemical Analysis
3838.56 Da
9.80
6.70
6.41
0.2161
-0.20
0.67
-0.27
53.98
47.10
0.1613
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1588.62
-17.03
67.0
54.0
121.0
265.0
6.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260473 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral
Streptococcus
PaperPubMed PMID: 2473036 | PubMed PMID: 3623703 PMID2473036;3623703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2473036/
RECORD: Rec_0262186 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 51.6%, T 19.4%, C 29.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antiviral Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0269699 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral
Pseudomonas aeruginosa
PaperPubMed PMID: 2473036 | PubMed PMID: 3623703 PMID2473036;3623703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2473036/
RECORD: Rec_0297529 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20050260715A1/en PatentUS 2005/0260715 A1
RECORD: Rec_0407651 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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