Peptide Database

Peptide NamePro-MCH

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC248H396N66O87S

DescriptionStandard

        ILLSASKSIRNSDDDMVFNTFRLGKAFQKEDTAEKSVIAPSLEEYKNDESS
    

Molecular Weight5726.25 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-3.23

Net Charge (pH 7.4) -3.45

Charge Density (pH 7.0) -0.0633

GRAVY Index-0.67

Hydrophobic Moment 0.59

Boman Index-0.15

Instability Index37.42

Aliphatic Index 72.75

Aromaticity 0.0784

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2531.32

LogP -29.62

H-bond Donors 87.0

H-bond Acceptors 85.0

Rotatable Bonds 199.0

Heavy Atoms 402.0

Ring Count 5.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011267 VERIFIED: YES

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyPro-MCH

Tax ID9597

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0054057 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyPro-MCH

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0209443 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyMelanin-concentrating hormone

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

RECORD: Rec_0289102 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/