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MYP_140535
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Basic Information
Indolicidin [W6K,W8K,W9L]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C85H136N24O14
Standard
Sequence
ILPWKKPKLPWRR
Physicochemical Analysis
1718.14 Da
12.00
4.76
4.55
0.3659
-1.17
0.50
-0.31
80.98
90.00
0.1538
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
619.59
0.23
22.0
19.0
52.0
123.0
7.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035301 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis IFO 3513
1.56 μg/mL
MIC
PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0047095 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli IFO 12734
12.5 μg/mL
MIC
PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0087051 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus IFO 12732
3.13 μg/mL
MIC
PaperStructure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin. PMID11695650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11695650/
RECORD: Rec_0111602 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
50 μM
Hemolysis
PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0228309 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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