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MYP_140533
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Basic Information
Cecropin A
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Gene expression inhibitor
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
37 amino acids
C184H312N52O47
Standard
Sequence
KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK
Physicochemical Analysis
4004.77 Da
10.39
5.76
5.54
0.1556
-0.07
0.80
0.04
16.52
108.11
0.0541
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1629.15
-12.59
55.0
53.0
141.0
283.0
4.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0328376 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSteiner H., Hultmark D., Engstrom A., Bennich H., Boman H. G.. Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature, 292, 246-248, 1981.
RECORD: Rec_0329670 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10795591/ PMID10795591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10795591/
RECORD: Rec_0332414 VERIFIED: YES
Provenance & Taxonomy
Hyalophora cecropia [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Serratia marcescens Db1121
4.4 μM
LC
PMID7140755;29925795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7140755/
RECORD: Rec_0336957 VERIFIED: YES
Provenance & Taxonomy
Hyalophora cecropia [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
SCC12
1 μM
IC50
PMID24661024 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24661024/
RECORD: Rec_0359453 VERIFIED: YES
Provenance & Taxonomy
Hyalophora cecropia [Animal]
Cecropin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. thuringiensis Bt11
80 μM
MIC
PMID7140755;27367675 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7140755/
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