‹ ›
MYP_140528
← PREVIOUS NEXT → BACK
Basic Information
NZ2114
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Wound healing/Regeneration ▸ Wound healing
Standard
40 amino acids
C191H280N56O54S6
Standard
Sequence
GFGCNGPWNEDDLRCHNHCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4417.00 Da
8.62
2.87
2.47
0.0718
-0.67
0.36
-0.05
25.49
29.25
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1776.67
-19.46
67.0
65.0
143.0
307.0
10.0
42.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0331266 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. pneumoniae CVCC2350
0.909 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0332155 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
8 μg/mL
MIC
PMID28476579;28848347 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28476579/
RECORD: Rec_0355545 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Wound healing
Also: S. pseudintermedius CGMCC 1.90024 or CGMCC 1.90005
0.23 μM
MIC
PaperHigh cerebrospinal fluid (CSF) penetration and potent bactericidal activity in CSF of NZ2114, a novel plectasin variant, during experimental pneumococcal meningitis.
RECORD: Rec_0372133 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. suis CVCC3928
0.028 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0390297 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory Wound healing
S-pullorum CVCC1789
>7.273 μM
MIC
PaperHigh cerebrospinal fluid (CSF) penetration and potent bactericidal activity in CSF of NZ2114, a novel plectasin variant, during experimental pneumococcal meningitis.
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 4 of 5