Peptide Database

Peptide NameCycloviolacin O23

Function Ontology

—

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC114H181N29O34S6

DescriptionStandard

        LPICGETCVLGTCYTPGCRCQYPIC
    

Molecular Weight2694.22 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0119

GRAVY Index0.54

Hydrophobic Moment 0.40

Boman Index0.23

Instability Index3.38

Aliphatic Index 74.00

Aromaticity 0.0800

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 978.79

LogP -9.70

H-bond Donors 39.0

H-bond Acceptors 40.0

Rotatable Bonds 78.0

Heavy Atoms 183.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0138140 VERIFIED: YES

Provenance & Taxonomy

OrganismSteinchisma laxum [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)