Peptide Database

Peptide NameBrevinin-1CHb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC222H366N60O68S3

DescriptionStandard

        GNAEEERRDEPDEMDVEVEKRFLPVIAGLAAKVLPKLFCAITKKC
    

Molecular Weight5059.84 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.0498

GRAVY Index-0.34

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index54.02

Aliphatic Index 88.89

Aromaticity 0.0444

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2069.47

LogP -16.22

H-bond Donors 71.0

H-bond Acceptors 69.0

Rotatable Bonds 173.0

Heavy Atoms 353.0

Ring Count 5.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366097 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates chiricahuensis [Animal]

FamilyBrevinin

Tax ID152345

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal