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MYP_140476
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Basic Information
GN-12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C74H101N21O10
Standard
Sequence
KWWKIWRWR
Physicochemical Analysis
1444.73 Da
12.00
3.76
3.55
0.4176
-1.77
0.32
-0.38
63.10
43.33
0.4444
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
535.12
2.00
22.0
14.0
43.0
105.0
8.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0107107 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
100 μg/mL
MIC
PMID26662856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26662856/
RECORD: Rec_0165318 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
173 μg/mL
IC50
PaperPubMed PMID: 25941221 PMID25941221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941221/
RECORD: Rec_0186874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: >400μg/ml
<10 %
Hemolysis
PaperPubMed PMID: 25941221 PMID25941221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941221/
RECORD: Rec_0262681 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25941221 PMID25941221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941221/
RECORD: Rec_0281228 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
25 μg/mL
MIC
PMID26662856 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26662856/
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