Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC373H611N103O112S12

DescriptionStandard

        MKTLRVAAVVAVLFALSGSTRMAEMEEPGDIDIPVELKAEEVSVDAMTSPYYRSREKRGIKCKFCCGCCTPGVCGVCCRF
    

Molecular Weight8715.24 Da

Isoelectric Point (pI)7.48

Net Charge (pH 7.0)0.44

Net Charge (pH 7.4) 0.08

Charge Density (pH 7.0) 0.0055

GRAVY Index0.19

Hydrophobic Moment 0.41

Boman Index0.04

Instability Index40.92

Aliphatic Index 75.50

Aromaticity 0.0625

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3424.09

LogP -33.86

H-bond Donors 129.0

H-bond Acceptors 125.0

Rotatable Bonds 288.0

Heavy Atoms 600.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061359 VERIFIED: NO

Provenance & Taxonomy

OrganismNeogobius melanostomus [Animal]

FamilyHepcidin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial

MethodQualitative functional evidence