Peptide Database

Peptide NameBeta-defensin 110 (Beta-defensin 10, DEFB-10; Defensin, beta 110; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC237H384N78O71S6

DescriptionStandard

        KKKYPEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCIRPGTHCCLQQ
    

Molecular Weight5654.45 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)3.88

Net Charge (pH 7.4) 3.47

Charge Density (pH 7.0) 0.0808

GRAVY Index-1.05

Hydrophobic Moment 0.56

Boman Index-0.32

Instability Index57.57

Aliphatic Index 58.96

Aromaticity 0.0625

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2473.66

LogP -27.75

H-bond Donors 91.0

H-bond Acceptors 83.0

Rotatable Bonds 193.0

Heavy Atoms 392.0

Ring Count 7.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062330 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Antiparasitic

RECORD: Rec_0115662 VERIFIED: NO