Peptide Database

Peptide NameConcanavalin-A

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibitory

Standard StatusStandard

Sequence Length290 amino acids

Chemical FormulaC1410H2190N366O437S5

DescriptionStandard

        MAISKKSSLFLPIFTFITMFLMVVNKVSSSTHETNALHFMFNQFSKDQKDLILQGDATTGTDGNLELTRVSSNGSPQGSSVGRALFYAPVHIWESSAVVASFDATFTFLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDANVIRNSTTIDFNAAYNADTIVAVELDTYPNTDIGDPNYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVGKRLSAVVSYPNGDSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKSNEIPDIATVV
    

Molecular Weight31420.99 Da

Isoelectric Point (pI)5.64

Net Charge (pH 7.0)-4.96

Net Charge (pH 7.4) -5.54

Charge Density (pH 7.0) -0.0171

GRAVY Index-0.03

Hydrophobic Moment 0.67

Boman Index0.12

Instability Index30.81

Aliphatic Index 88.07

Aromaticity 0.0966

Extinction Coeff. Reduced 33920.00

Extinction Coeff. Oxidized 33920.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077608 VERIFIED: YES

Provenance & Taxonomy

OrganismCanavalia gladiata [Plant]

FamilyLectin

Tax ID3824

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsN-glycosylation Asn152

Bio-Activity Profile

Function

Antiviral Reverse transcriptase inhibitory Anti-HIV-1

TargetHuman immunodeficiency virus type-1(HIV-1)

Activity35 μM

MethodIC50