Peptide Database

Peptide NameEsculentin-2N protein

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC311H502N84O104S4

DescriptionStandard

        GTINFSFCEEERNADEEEEGEVQEEEVKRGIFSLIKGAAKVVAKGLGKEVGKFGLDLMACKVTNQC
    

Molecular Weight7210.07 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-5.24

Net Charge (pH 7.4) -5.52

Charge Density (pH 7.0) -0.0794

GRAVY Index-0.39

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index36.25

Aliphatic Index 75.30

Aromaticity 0.0606

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3079.33

LogP -31.51

H-bond Donors 106.0

H-bond Acceptors 103.0

Rotatable Bonds 257.0

Heavy Atoms 503.0

Ring Count 4.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0052533 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Tax ID8409

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal