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MYP_140319
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Basic Information
Tyrocidine B1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C69H92N14O14
Standard
Sequence
FPWFNQYVKL
Physicochemical Analysis
1341.55 Da
8.59
0.76
0.55
0.0758
-0.11
0.44
0.26
-1.07
68.00
0.4000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
464.65
0.40
15.0
15.0
38.0
97.0
6.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0293963 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Micrococcus luteus NCTC 8340
4.2
IC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0297725 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Hemolytic
human red blood cells
8.6 μM
HC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0355023 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Listeria monocytogenes B73-MR1
10.0
MIC
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
RECORD: Rec_0379723 VERIFIED: YES
Provenance & Taxonomy
Bacillus aneurinolyticus [Bacterium]; Bacillus brevis [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Listeria monocytogenes B73
8.1
IC50
PMID17462586;19586775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17462586/
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