Peptide Database

Peptide NameLantibiotic actagardine (Gardimycin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC299H469N79O97S5

DescriptionStandard

        MSALAIEKSWKDVDLRDGATSHPAGLGFGELTFEDLREDRTIYAASSGWVCTLTIECGTVICAC
    

Molecular Weight6882.72 Da

Isoelectric Point (pI)4.45

Net Charge (pH 7.0)-5.44

Net Charge (pH 7.4) -5.78

Charge Density (pH 7.0) -0.0849

GRAVY Index0.14

Hydrophobic Moment 0.48

Boman Index0.13

Instability Index65.74

Aliphatic Index 85.47

Aromaticity 0.0781

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2801.59

LogP -28.89

H-bond Donors 104.0

H-bond Acceptors 98.0

Rotatable Bonds 224.0

Heavy Atoms 480.0

Ring Count 9.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304796 VERIFIED: YES

Provenance & Taxonomy

OrganismActinoplanes garbadinensis [other]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram Positive Bacteria

RECORD: Rec_0358060 VERIFIED: NO