Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 6.5

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC177H282N52O56S8

DescriptionStandard

        DEAIRCTGTKDCYIPCRYITGCFNSRCINKSCKCYGCT
    

Molecular Weight4290.97 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.35

Charge Density (pH 7.0) 0.0705

GRAVY Index-0.29

Hydrophobic Moment 0.64

Boman Index-0.13

Instability Index33.11

Aliphatic Index 43.68

Aromaticity 0.1053

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1775.14

LogP -22.28

H-bond Donors 72.0

H-bond Acceptors 67.0

Rotatable Bonds 139.0

Heavy Atoms 293.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405512 VERIFIED: YES

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-27; 12-32; 16-34; 22-37

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense