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MYP_140248
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Basic Information
Sakacin P
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
18 amino acids
C90H128N26O26S2
Standard
Sequence
KYYGNGVHCGKHSCTVDW
Physicochemical Analysis
2054.27 Da
8.04
0.91
0.57
0.0507
-0.78
0.38
-0.01
21.67
32.22
0.1667
8480.00
8605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
844.52
-8.76
32.0
31.0
63.0
144.0
6.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033968 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus sakei [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Enterococcus faecalis LMG2708
8.8 ng/mL
Concentration causing 50% growth inhibition
PMID8636023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8636023/
RECORD: Rec_0096833 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus sakei [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Pediococcus pentosaceus LMG2722
2500 ng/mL
Concentration causing 50% growth inhibition
PMID8636023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8636023/
RECORD: Rec_0133387 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus sakei [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactobacillus sp. LMG2003
35 ng/mL
Concentration causing 50% growth inhibition
PMID8636023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8636023/
RECORD: Rec_0226710 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled bacterial growth assay (OD at 4.5 h; statistical hit call)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0275999 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus sakei [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactobacillus sake LTH673 (Bac1)
1200 ng/mL
Concentration causing 50% growth inhibition
PMID8636023 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8636023/
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