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MYP_140226
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Basic Information
Ranalexin-Vb (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
20 amino acids
C100H167N23O23S2
Standard
Sequence
FLGGLFKLVPSVICAVTKKC
Physicochemical Analysis
2123.67 Da
9.39
2.74
2.50
0.1369
1.26
0.48
0.39
18.93
126.50
0.1000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
725.95
-3.34
27.0
28.0
69.0
148.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007562 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
14-20
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
12 μM
MIC
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
RECORD: Rec_0030191 VERIFIED: NO
Provenance & Taxonomy
Rana virgatipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0108008 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0122067 VERIFIED: NO
Provenance & Taxonomy
Rana virgatipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
RECORD: Rec_0171137 VERIFIED: YES
Provenance & Taxonomy
Lithobates virgatipes [Animal]
Ranalexin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
14-20
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
12.5 μM
MIC
PaperJ.M. Conlon et al. / Regulatory Peptides 131 (2005) 38-45. Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana)
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