Peptide Database

Peptide NamekEA1x8L

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC120H210N56O34S3

DescriptionStandard

        ACSDRFRNCPADEALCGRRRRRRRR
    

Molecular Weight3077.50 Da

Isoelectric Point (pI)11.63

Net Charge (pH 7.0)6.77

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.2708

GRAVY Index-1.69

Hydrophobic Moment 0.37

Boman Index-0.93

Instability Index200.34

Aliphatic Index 27.60

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1547.15

LogP -21.38

H-bond Donors 63.0

H-bond Acceptors 44.0

Rotatable Bonds 105.0

Heavy Atoms 213.0

Ring Count 2.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142105 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilykEA1x8L

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Other ModsAll cysteines were capped with iodoacetamide

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0228897 VERIFIED: YES