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MYP_140157
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Basic Information
MIP(M11A)
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C82H112N20O18
Standard
Sequence
PRFWEYWLRLAE
Physicochemical Analysis
1665.89 Da
6.70
-0.03
-0.10
-0.0026
-0.71
0.79
-0.05
20.57
73.33
0.3333
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
619.64
0.16
24.0
18.0
49.0
120.0
7.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068370 VERIFIED: YES
Provenance & Taxonomy
E3 ubiquitin-protein ligase [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 21423613 PMID21423613 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21423613/
RECORD: Rec_0076114 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0099990 VERIFIED: YES
Provenance & Taxonomy
E3 ubiquitin-protein ligase [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
--
IC50
PaperPubMed PMID: 21423613 PMID21423613 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21423613/
RECORD: Rec_0374945 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 66.7%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antitumor
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0378517 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
E3 ubiquitin-protein ligase
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HCT-116-p53+/+
0.4 μM
IC50
PMID21423613 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21423613/
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