Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC211H365N61O70S9

DescriptionStandard

        MDIVVKKQDNVVQPNVTSKSLCTPSCITGVLMCLTQNSCVSCNSCIRC
    

Molecular Weight5165.11 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.43

Net Charge (pH 7.4) 1.11

Charge Density (pH 7.0) 0.0298

GRAVY Index0.35

Hydrophobic Moment 0.46

Boman Index0.07

Instability Index55.68

Aliphatic Index 91.04

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2131.93

LogP -28.91

H-bond Donors 79.0

H-bond Acceptors 81.0

Rotatable Bonds 172.0

Heavy Atoms 351.0

Ring Count 2.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0196357 VERIFIED: NO

Provenance & Taxonomy

OrganismParageobacillus galactosidasius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear lantibiotic precursor [Linear]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

MethodQualitative functional evidence