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MYP_140150
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Basic Information
Antimicrobial peptide, Pelophylaxin-4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Standard
13 amino acids
C73H118N14O15
Standard
Sequence
ILPFLAGLFSKIL
Physicochemical Analysis
1431.80 Da
8.75
0.76
0.55
0.0584
1.92
0.40
0.69
61.96
187.69
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
1.26
15.0
16.0
45.0
102.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022198 VERIFIED: NO
Provenance & Taxonomy
Rana plancyi fukiensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
PaperPelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by shotgun cDNA cloning and sequence analysis. PMID16139927
RECORD: Rec_0124924 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled bacterial growth assay (OD at 4.5 h; statistical hit call)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0178113 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 53.8%, E 0.0%, T 23.1%, C 23.1% [Linear]
canonical L-amino-acid peptide [L]
-
Amidation
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0281432 VERIFIED: NO
Provenance & Taxonomy
Pelophylax fukienensis [Animal]
Pelophylaxin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperT. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs PMID16139927 Evidence URLhttps://www.uniprot.org/uniprotkb/Q2WCN5/entry
RECORD: Rec_0291926 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 46.2%, E 0.0%, T 38.5%, C 15.4% [Linear]
canonical L-amino-acid peptide [L]
-
Amidation
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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