Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 23.1

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC157H260N50O46S9

DescriptionStandard

        AAAISCVGSPECPPKCRAQGCKNGKCMNRKCKCYYC
    

Molecular Weight3872.64 Da

Isoelectric Point (pI)9.07

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.1587

GRAVY Index-0.41

Hydrophobic Moment 0.56

Boman Index-0.16

Instability Index60.21

Aliphatic Index 30.00

Aromaticity 0.0556

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1556.84

LogP -20.31

H-bond Donors 61.0

H-bond Acceptors 61.0

Rotatable Bonds 126.0

Heavy Atoms 262.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255763 VERIFIED: YES

Provenance & Taxonomy

OrganismVaejovis mexicanus smithi [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide6-26; 12-31; 16-33; 21-36

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense