Peptide Database

Peptide NameBrevinin-1CHa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC220H363N59O67S3

DescriptionStandard

        NAEEERRDEPDEMDVEVEKRFLPIIAGVAAKVLPKLFCAITKKC
    

Molecular Weight5002.79 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.0509

GRAVY Index-0.32

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index52.58

Aliphatic Index 90.91

Aromaticity 0.0455

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2040.37

LogP -15.34

H-bond Donors 70.0

H-bond Acceptors 68.0

Rotatable Bonds 171.0

Heavy Atoms 349.0

Ring Count 5.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021453 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates chiricahuensis [Animal]

FamilyBrevinin

Tax ID152345

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0311331 VERIFIED: NO