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MYP_140114
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Basic Information
DSE (Ctx-Ha peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
41 amino acids
C212H331N55O50
Standard
Sequence
GWLDVAKKIGKAAFNVAKNFLFNKAVNFAAKGIKKAVDLWG
Physicochemical Analysis
4450.23 Da
10.22
5.75
5.54
0.1404
0.18
0.67
0.16
3.45
95.37
0.1463
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1714.02
-10.77
58.0
56.0
151.0
317.0
8.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080678 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacterium: Staphylococcus aureus
8.9 μM
MIC
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0088450 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 90.2%, E 0.0%, T 0.0%, C 9.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0095876 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
0.6±0.1 μM
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/22391524/ PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0100682 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
53.3 μM
MIC
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0101837 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
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