Peptide Database

Peptide NameLIGHT

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin-related activity

Standard StatusStandard

Sequence Length240 amino acids

Chemical FormulaC1182H1864N336O334S7

DescriptionStandard

        MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLLLLMGAGLAVQGWFLLQLHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQLGLAFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEELELLVSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFGAFMV
    

Molecular Weight26349.95 Da

Isoelectric Point (pI)9.09

Net Charge (pH 7.0)4.11

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.0171

GRAVY Index0.01

Hydrophobic Moment 0.82

Boman Index0.09

Instability Index45.91

Aliphatic Index 98.21

Aromaticity 0.0875

Extinction Coeff. Reduced 44920.00

Extinction Coeff. Oxidized 45045.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113009 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsN-linked glycosylation of asparagine residue at position 102; predicted disulphide bond between cysteine resisues at positons 154 and 187

Bio-Activity Profile

Function

Toxin-related activity

Targetherpes virus entry mediator (Human); lymphotoxin β receptor (Human); decoy receptor 3 (Human)