Peptide Database

Peptide NameBeta-defensin 108B (Beta-defensin 8) (BD-8) (DEFB-8) (hBD-8) (Defensin; beta 108) (Defensin; beta 108B)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC368H588N104O100S8

DescriptionStandard

        MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCLPLGHQPRIESTTPKKD
    

Molecular Weight8325.76 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0360

GRAVY Index-0.07

Hydrophobic Moment 0.43

Boman Index-0.00

Instability Index54.86

Aliphatic Index 80.14

Aromaticity 0.0822

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3256.78

LogP -29.05

H-bond Donors 117.0

H-bond Acceptors 113.0

Rotatable Bonds 273.0

Heavy Atoms 580.0

Ring Count 14.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425203 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found