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MYP_139974
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Basic Information
Dermaseptin-PT9 (DPT9).
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C118H193N31O33S
Standard
Sequence
GLWSKIKDAAKTAGKAALGFVNEMV
Physicochemical Analysis
2606.05 Da
9.53
1.76
1.55
0.0704
0.18
0.65
0.17
8.88
90.00
0.0800
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1039.74
-8.70
36.0
36.0
89.0
183.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0289536 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
16 μM
MIC
PMID31635388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31635388/
RECORD: Rec_0338056 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus NCTC 12493
32 μM
MIC
PMID31635388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31635388/
RECORD: Rec_0341769 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC 10788
16 μM
MBIC
PMID31635388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31635388/
RECORD: Rec_0394135 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus NCTC 12493
32 μM
MBIC
PMID31635388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31635388/
RECORD: Rec_0405701 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa tarsius [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus NCTC 10788
16 μM
MIC
PaperA Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
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