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MYP_139974
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Basic Information
Dermaseptin-PT9 (DPT9).
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
25 amino acids
C118H193N31O33S
Standard
Sequence
GLWSKIKDAAKTAGKAALGFVNEMV
Physicochemical Analysis
2606.05 Da
9.53
1.76
1.55
0.0704
0.18
0.65
0.17
8.88
90.00
0.0800
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1039.74
-8.70
36.0
36.0
89.0
183.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0177639 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC 10788
16 μM
MIC
PMID31635388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31635388/
RECORD: Rec_0207545 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
210 μM
HC50
PMID31635388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31635388/
RECORD: Rec_0208512 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa tarsius [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Klebsiella pneumoniae ATCC 43816
8 μM
MIC
PaperA Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
RECORD: Rec_0216829 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa tarsius [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
2-4
MIC
PaperA Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
RECORD: Rec_0226573 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Phyllomedusa tarsius [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Enterococcus faecalis NCTC 12697
16 μM
MIC
PaperA Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
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