Peptide Database

Peptide NameNosiheptide precursor [Cleaved into: Nosiheptide (NOS) (Antibiotic 9671-RP) (Multhiomycin)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC216H350N56O86S8

DescriptionStandard

        MDAAHLSDLDIDALEISEFLDESRLEDSEVVAKVMSASCTTCECCCSCSS
    

Molecular Weight5363.93 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.45

Net Charge (pH 7.4) -10.82

Charge Density (pH 7.0) -0.2090

GRAVY Index0.18

Hydrophobic Moment 0.37

Boman Index0.05

Instability Index74.36

Aliphatic Index 82.00

Aromaticity 0.0200

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2275.95

LogP -29.04

H-bond Donors 85.0

H-bond Acceptors 85.0

Rotatable Bonds 181.0

Heavy Atoms 366.0

Ring Count 2.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019003 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces actuosus [Animal]

FamilyThiocillin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Hemolytic

TargetNo Target Organism Found