Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC371H604N106O93S8

DescriptionStandard

        MRVFHSILGILALLSIVPQARTLFFKDTCSLKGYTCRMKCNADEHAIRYCTDWTICCKEKKIRPKKRKKW
    

Molecular Weight8293.94 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)10.61

Net Charge (pH 7.4) 10.18

Charge Density (pH 7.0) 0.1516

GRAVY Index-0.27

Hydrophobic Moment 0.58

Boman Index-0.12

Instability Index13.55

Aliphatic Index 80.86

Aromaticity 0.1000

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3249.16

LogP -24.80

H-bond Donors 124.0

H-bond Acceptors 114.0

Rotatable Bonds 282.0

Heavy Atoms 578.0

Ring Count 13.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005169 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Animal]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0190315 VERIFIED: NO