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MYP_139907
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Basic Information
ToAMP3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
42 amino acids
C180H300N52O56S10
Standard
Sequence
ANKCIIDCMKVKTTCGDECKGAGFKTGGCALPPDIMKCCHNC
Physicochemical Analysis
4409.27 Da
8.21
1.80
1.44
0.0430
-0.03
0.46
0.02
44.30
51.19
0.0238
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1719.71
-20.55
65.0
69.0
148.0
298.0
4.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044838 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0058550 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Cysteine rich peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pythium debaryanum
PaperPubMed PMID 22640720 PMID22640720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22640720/
RECORD: Rec_0079252 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum
5.7 μM
IC50
PaperDiscovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers
RECORD: Rec_0116235 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Cysteine rich peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Botrytis cinerea
PaperPubMed PMID 22640720 PMID22640720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22640720/
RECORD: Rec_0141418 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Cysteine rich peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Fusarium graminearum
PaperPubMed PMID 22640720 PMID22640720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22640720/
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