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MYP_139906
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C59H106N16O17
Standard
Sequence
GILDAIKAIAKAAG
Physicochemical Analysis
1311.57 Da
8.59
0.76
0.55
0.0542
1.01
0.66
0.38
10.91
147.14
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
530.96
-4.02
18.0
18.0
45.0
92.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0144817 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas albomarginatus [Animal]
Hylaseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
PaperM.V. Prates et al. / The Journal of Biological Chemistry 279 (2004) 13018-13026. The NMR-derived solution structure of a new cationic antimicrobial peptide from the skin secretion of the anuran Hyla punctata Evidence URLhttps://www.uniprot.org/uniprotkb/P84292/entry
RECORD: Rec_0147236 VERIFIED: YES
Provenance & Taxonomy
Hyla punctata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 27853
48.8-64 μM
MIC
PaperThe NMR-derived solution structure of a new cationic antimicrobial peptide from the skin secretion of the anuran Hyla punctata.
RECORD: Rec_0149900 VERIFIED: YES
Provenance & Taxonomy
Hyla punctata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
24.4-32 μg/mL
MIC
PMID14715660;32828849 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14715660/
RECORD: Rec_0178326 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas punctatus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans wt
195.2-256.0 μg/mL
MIC
PMID14715660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14715660/
RECORD: Rec_0195795 VERIFIED: NO
Provenance & Taxonomy
Hypsiboas punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2020/0048303 A1 Evidence URLhttps://patents.google.com/patent/US20200048303A1/en PatentUS 2020/0048303 A1
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