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MYP_139858
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
12 amino acids
C60H93N15O15
Standard
Sequence
EPVLGPVRGPFP
Physicochemical Analysis
1264.47 Da
6.10
-0.16
-0.33
-0.0136
-0.02
0.37
0.21
82.34
80.83
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
447.46
-2.25
13.0
15.0
32.0
90.0
5.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014924 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
99130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
ACE
PaperACE-inhibitory peptides in sodium-reduced cheese with probiotic: identification, in silico prediction and molecular interaction. LWT 200:116198 (2024).
RECORD: Rec_0030499 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAnalysis of the Endogenous Peptide Profile of Milk: Identification of 248 Mainly Casein-Derived Peptides
RECORD: Rec_0033447 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
790 μM
IC50
PaperCasein fermentate of Lactobacillus animalis DPC6134 contains a range of novel propeptide angiotensin-converting enzyme inhibitors PMID17483275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17483275/
RECORD: Rec_0135391 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0165635 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
89462
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Antioxidant Antimicrobial Antibacterial
PaperPMID 17483275; Characterization of the microbial diversity and chemical composition of Gouda cheese made by potential probiotic strains as an adjunct starter culture; Identification of antihypertensive peptides derived from low molecular weight casein hydrolysates generated during fermentation by Bifidobacterium longum KACC 91563 PMID17483275;27606488;26877633 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17483275/
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