Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC295H467N87O83S5

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMDTGGVMALPEETGAHIPERLRPYDVMSKKRMPHK
    

Molecular Weight6720.72 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.0344

GRAVY Index-0.74

Hydrophobic Moment 0.54

Boman Index-0.09

Instability Index78.27

Aliphatic Index 59.49

Aromaticity 0.0678

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2704.40

LogP -23.73

H-bond Donors 95.0

H-bond Acceptors 93.0

Rotatable Bonds 220.0

Heavy Atoms 470.0

Ring Count 14.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403718 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus masou [Animal]

FamilyProgonadoliberin

Tax ID8020

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour