Peptide Database

Peptide NameCecropin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC184H315N55O46S

DescriptionStandard

        RWKIFKKIEKMGRNIRDGIVKAGPAIEVLGSAKAVGK
    

Molecular Weight4065.88 Da

Isoelectric Point (pI)10.71

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1827

GRAVY Index-0.25

Hydrophobic Moment 0.91

Boman Index-0.07

Instability Index59.58

Aliphatic Index 97.57

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1660.98

LogP -12.68

H-bond Donors 59.0

H-bond Acceptors 54.0

Rotatable Bonds 145.0

Heavy Atoms 286.0

Ring Count 4.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0300751 VERIFIED: YES

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)