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MYP_139810
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Basic Information
Lingual antimicrobial peptide (LAP, beta defensin, cattle, ruminant, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
42 amino acids
C186H332N72O53S7
Standard
Sequence
QGVRNSQSCRRNKGICVPIRCPGSMRQIGTCLGAQVKCCRRK
Physicochemical Analysis
4649.53 Da
10.85
9.70
9.40
0.2309
-0.57
0.49
-0.33
75.55
60.24
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2089.66
-29.65
81.0
70.0
161.0
318.0
2.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014933 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-38; 16-31; 21-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID7886453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7886453/
RECORD: Rec_0140806 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-38; 16-31; 21-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans 14053
32-63 μg/mL
MIC
PMID7886453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7886453/
RECORD: Rec_0172633 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-38; 16-31; 21-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli D31
16-32 μg/mL
MIC
PMID7886453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7886453/
RECORD: Rec_0178314 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-38; 16-31; 21-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacterium: Staphylococcus aureus 29213
63-125 μg/mL
MIC
PMID7886453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7886453/
RECORD: Rec_0276829 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-38; 16-31; 21-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa 27853
63-125 μg/mL
MIC
PMID7886453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7886453/
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