Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC367H602N92O104S3

DescriptionStandard

        MDFSSGHQFALDLSTNLGISRKTAYVAIGVIMTTGDVLTILSLLAVVLGGTGLITAAMVATAKKLAKKYGKKYAAEW
    

Molecular Weight8063.45 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)3.58

Net Charge (pH 7.4) 3.30

Charge Density (pH 7.0) 0.0465

GRAVY Index0.56

Hydrophobic Moment 0.64

Boman Index0.27

Instability Index8.10

Aliphatic Index 112.86

Aromaticity 0.0779

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3122.49

LogP -26.98

H-bond Donors 112.0

H-bond Acceptors 112.0

Rotatable Bonds 271.0

Heavy Atoms 566.0

Ring Count 8.0

Amide Bonds 78.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0422107 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus swezeyi [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal