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MYP_139737
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Basic Information
Cm-CATH2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
33 amino acids
C181H307N69O38S
Standard
Sequence
RRSRFGRFFKKVRKQLGRVLRHSRITVGGRMRF
Physicochemical Analysis
4089.88 Da
12.00
12.84
12.59
0.3892
-0.89
0.86
-0.53
62.63
61.82
0.1212
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1824.04
-18.12
72.0
53.0
145.0
289.0
5.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0189131 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID31121185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31121185/
RECORD: Rec_0192550 VERIFIED: YES
Provenance & Taxonomy
Chelonia mydas [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
MIC 9.38
18.75 μg/mL
MIC
PaperDiversity, immunoregulatory action and structure-activity relationship of green sea turtle cathelicidins
RECORD: Rec_0195226 VERIFIED: YES
Provenance & Taxonomy
Chelonia mydas [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Escherichia coli ATCC 25922 and clinical strains
4.69-9.38 μg/mL
MIC
PaperDiversity, immunoregulatory action and structure-activity relationship of green sea turtle cathelicidins
RECORD: Rec_0203470 VERIFIED: YES
Provenance & Taxonomy
Chelonia mydas [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
aquatic bacteria Gram- V. alginolyticus
4.58 μM
MIC
PaperDiversity, immunoregulatory action and structure-activity relationship of green sea turtle cathelicidins
RECORD: Rec_0214110 VERIFIED: YES
Provenance & Taxonomy
Chelonia mydas [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans (CI)
18.75 μg/mL
MIC
PMID31121185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31121185/
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