Peptide Database

Peptide NameSLAY-screened peptide P3620

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC100H144N26O28S

DescriptionStandard

        PSGCTSNFNWTLIAAPLFNH
    

Molecular Weight2190.44 Da

Isoelectric Point (pI)7.12

Net Charge (pH 7.0)0.04

Net Charge (pH 7.4) -0.09

Charge Density (pH 7.0) 0.0018

GRAVY Index0.13

Hydrophobic Moment 0.24

Boman Index0.29

Instability Index24.84

Aliphatic Index 68.50

Aromaticity 0.1500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 848.10

LogP -9.17

H-bond Donors 30.0

H-bond Acceptors 30.0

Rotatable Bonds 63.0

Heavy Atoms 155.0

Ring Count 7.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239499 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/