Peptide Database

Peptide NameUnnamed

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC359H534N104O108S

DescriptionStandard

        SWKPRSQQPDAPLGTGANRDLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF
    

Molecular Weight8066.78 Da

Isoelectric Point (pI)5.17

Net Charge (pH 7.0)-4.26

Net Charge (pH 7.4) -4.64

Charge Density (pH 7.0) -0.0600

GRAVY Index-1.25

Hydrophobic Moment 0.45

Boman Index-0.15

Instability Index75.87

Aliphatic Index 49.58

Aromaticity 0.0845

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3363.68

LogP -32.89

H-bond Donors 109.0

H-bond Acceptors 108.0

Rotatable Bonds 252.0

Heavy Atoms 572.0

Ring Count 23.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047180 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0108413 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGastrin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods38:Pyrrolidone carboxylic acid; 55:Pyrrolidone carboxylic acid; 66:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0384468 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGastrin/cholecystokinin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsGln38 Pyroglutamylation; Gln55 Pyroglutamylation; Tyr66 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide