Peptide Database

Peptide NameMtDef5B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC229H376N76O64S7

DescriptionStandard

        KLCERRSKTWSGPCLISGNCKRQINVEHATSGACHRQGIGFACFCKKKC
    

Molecular Weight5442.36 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.86

Net Charge (pH 7.4) 7.45

Charge Density (pH 7.0) 0.1605

GRAVY Index-0.49

Hydrophobic Moment 0.42

Boman Index-0.17

Instability Index59.82

Aliphatic Index 51.84

Aromaticity 0.0612

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2296.54

LogP -28.50

H-bond Donors 89.0

H-bond Acceptors 81.0

Rotatable Bonds 186.0

Heavy Atoms 376.0

Ring Count 7.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294323 VERIFIED: YES

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetClavibacter michiganensis

Activity12 μM

MethodMIC

RECORD: Rec_0321427 VERIFIED: YES