‹ ›
MYP_139535
← PREVIOUS NEXT → BACK
Basic Information
S12A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C71H113N15O18
Standard
Sequence
GLFDIIKKIAEAF
Physicochemical Analysis
1464.75 Da
6.07
-0.24
-0.45
-0.0183
0.87
0.71
0.36
5.66
135.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
539.16
-0.85
18.0
18.0
50.0
104.0
2.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0060728 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis PCM 2673
64 μg/mL
MIC
PMID30569430 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30569430/
RECORD: Rec_0064344 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 10231
32 μg/mL
MIC
Fetal bovine serum: 37℃，in fetal bovine serum, 77% remaining after 6 h
PaperMigoń D, Jaśkiewicz M, Neubauer D, Bauer M, Sikorska E, Kamysz E, Kamysz W. Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2. Probiotics Antimicrob Proteins. 2019 Sep;11(3):1042-1054. PMID:30569430 https://pubmed.ncbi.nlm.nih.gov/30569430/ PMID30569430 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30569430/
RECORD: Rec_0067576 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 9027
>512 μg/mL
MIC
Fetal bovine serum: 37℃，in fetal bovine serum, 77% remaining after 6 h
PaperMigoń D, Jaśkiewicz M, Neubauer D, Bauer M, Sikorska E, Kamysz E, Kamysz W. Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2. Probiotics Antimicrob Proteins. 2019 Sep;11(3):1042-1054. PMID:30569430 https://pubmed.ncbi.nlm.nih.gov/30569430/ PMID30569430 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30569430/
RECORD: Rec_0095976 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 10231
32 μg/mL
MIC
PMID30569430 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30569430/
RECORD: Rec_0123357 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
No hemolytic activity at 256microg/ml
256 μg/mL
Hemolysis
PMID30569430 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30569430/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3