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MYP_139453
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Basic Information
TetraF2W-RK
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
8 amino acids
C68H88N16O9
Standard
Sequence
WWWLRKIW
Physicochemical Analysis
1273.53 Da
11.00
1.76
1.55
0.2199
-0.46
0.56
0.21
37.64
97.50
0.5000
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
418.10
4.17
17.0
11.0
35.0
93.0
8.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251494 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2019/0048052 A1 Evidence URLhttps://patents.google.com/patent/US20190048052A1/en PatentUS 2019/0048052 A1
RECORD: Rec_0326183 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli K12
25 μM
MIC
PaperMishra B, Lushnikova T, Golla RM, Wang X, Wang G. Design and surface immobilization of short anti-biofilm peptides. Acta Biomater. 2017;49:316-328. doi:10.1016/j.actbio.2016.11.061 PMID27915018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27915018/
RECORD: Rec_0328022 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
6.20 μM
MIC
PMID28731688;33804947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28731688/
RECORD: Rec_0341619 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 10231
12.5 μM
MIC
PaperMishra B, Lushnikova T, Golla RM, Wang X, Wang G. Design and surface immobilization of short anti-biofilm peptides. Acta Biomater. 2017;49:316-328. doi:10.1016/j.actbio.2016.11.061 PMID27915018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27915018/
RECORD: Rec_0351052 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
3.1 μM
MIC
PMID28731688;33804947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28731688/
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